Selective delivery of photothermal nanoparticles to tumors using mesenchymal stem cells as Trojan horses
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The main challenge of cancer treatment is to avoid or minimize systemic side effects in off-target tissues. Mesenchymal stem cells (MSCs) can be used as therapeutical carriers because of their ability to migrate and incorporate into inflammation areas including tumors. Here, this homing ability is exploited by carrying therapeutic nanoparticles (Hollow Gold Nanoparticles (HGNs)) following a “Trojan-horse” strategy.
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NFP Research Area: nanomedicine: nanomaterials-as-vectors-for-drug-delivery