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Cu-releasing nanoparticles induce the catalytic transamination of amino acids and GSSG under tumor microenvironment conditions

  • 04/07/2023
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Catalytic cancer therapy exploits the tumor microenvironment (TME) to target cancer cells by leveraging molecules already present in the TME. Currently, only a few processes have been explored for cancer therapy, including glucose and glutathione oxidation, generation of reactive oxygen species (ROS), and alleviation of tumor hypoxia. Amino groups, which are abundant in biological environments, […]

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On-chip monitoring of toxic gases: capture and label-free SERS detection with plasmonic mesoporous sorbents

  • 22/06/2023
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The evaluation of toxic gas molecules spread in air at low concentration on field requires a robust microfluidic platform combined with analytical technique that can be portable and able to detect and identify the molecules. We integrate a 3D plasmonic architecture based on closely packed mesoporous silica (MCM48) nanospheres decorated by Au nanoparticles arrays, denoted […]

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Solar Energy Storage Using a Cu2O-TiO2 Photocathode in a Lithium Battery

  • 12/04/2023
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A Cu2O-TiO2 photoelectrode is proposed for simultaneous solar light energy harvesting and storing of electrochemical energy in an adapted lithium coin cell. The p-type Cu2O semiconductor layer is the light harvester component of the photoelectrode and the TiO2 film performs as the capacitive layer. The rationale of the energy scheme shows that the photocharges generated […]

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Microwave-Driven Exfoliation of Bulk 2H-MoS2 after Acetonitrile Prewetting Produces Large-Area Ultrathin Flakes with Exceptionally High Yield

  • 24/03/2023
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2D materials display exciting properties in numerous fields, but the development of applications is hindered by the low yields, high processing times, and impaired quality of current exfoliation methods. In this work we have used the excellent MW absorption properties of MoS2 to induce a fast heating that produces the near-instantaneous evaporation of an adsorbed, […]

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Double redox aqueous capacitor with high energy output

  • 01/03/2023
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The paper puts forward the concept of double redox electrochemical capacitor operating in an aqueous electrolyte. It combines the redox activity of sulphur from Bi2S3 nanocrystals combined with the reactions of iodides which take place at opposite electrode. This combination effectively boosts the capacitance (275 F g-1), and the energy density of the device thanks […]

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In Cellulo Bioorthogonal Catalysis by Encapsulated AuPd Nanoalloys: Overcoming Intracellular Deactivation

  • 13/02/2023
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Bioorthogonal metallocatalysis has opened up a xenobiotic route to perform nonenzymatic catalytic transformations in living settings. Despite their promising features, most metals are deactivated inside cells by a myriad of reactive biomolecules, including biogenic thiols, thereby limiting the catalytic functioning of these abiotic reagents. Here we report the development of cytocompatible alloyed AuPd nanoparticles with […]

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Unveiling the interplay between homogeneous and heterogeneous catalytic mechanisms in copper-iron nanoparticles working under chemically relevant tumour conditions

  • 21/06/2022
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In this work we have designed a bimetallic catalyst nanoparticle containing Cu and Fe species and we describe how homogeneous and heterogeneous processes involving gluthatione are coupled and fostered in the tumor microenvironment. Full article here. NFP Research Area: nanomedicine: catalysis against cancer

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Formamidinium halide salts as precursors of carbon nitrides

  • 17/06/2022
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Pyrolysis of formamidinium halide salts (FAI, FABr) results in a new type of amorphous carbon nitride materials with a mass fraction of 40–50% nitrogen content. Pyrolysis temperature drives final chemical composition, morphology, optical and electrical properties of the material independently of the halide precursor and identi­fying triazine ring, instead of typical heptazine unit, as the […]

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Transfer of photothermal nanoparticles using stem cell derived small extracellular vesicles for in vivo treatment of primary and multinodular tumours

  • 08/03/2022
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The main current challenges in oncology are (1) avoiding systemic side effects in therapy, and (2) developing alternative treatment strategies for metastatic tumours. Nanomedicine was assumed to provide answers to these issues, but delivering enough therapeutic nanoparticles (NPs) to tumours still remains a huge challenge in nanomaterials-based treatments. Extracellular vesicles (EVs) play a key role […]

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